利用50K芯片数据分析中国11个地方绵羊群体的遗传结构

doi:10.11843/j.issn.0366-6964.2016.05.006

摘要/Abstract

摘要：

旨在构建我国绵羊群体遗传结构的精细图谱，为我国绵羊遗传资源的保存、利用提供依据。利用乌珠穆沁羊、湖羊、同羊、大尾寒羊、罗布羊、哈萨克羊、多浪羊、迪庆羊、青海臧羊、四川藏羊、西藏藏羊共计11个地方绵羊品种（资源）的Illumina Ovine SNP 50K芯片数据，应用NETVIEW、PCA、STRUCTURE、NJ树等方法对群体结构进行分析。结果表明，乌珠穆沁羊与除罗布羊以外的蒙古系绵羊均有直接遗传关系，与罗布羊有间接的遗传关系。罗布羊与哈萨克系绵羊有较近的遗传关系，而哈萨克系的哈萨克羊与多浪羊存在较远的遗传关系。迪庆羊能够与藏系绵羊分离开，西藏地区藏羊能够与其他地区的藏羊分开，青海、四川的藏羊不能分开。结果提示，NETVIEW计算时间短，且基本能够反映史实，因而可以作为未来群体结构分析的工具；乌珠穆沁羊是此次试验选用的蒙古系绵羊中最古老的品种；蒙古系的罗布羊因混有哈萨克系绵羊的血统而与新疆地区的绵羊聚在一起；不同地区的藏羊存在着分化趋势，但分化并不严重。

Abstract:

The study aimed to construct the fine-scale profile for population structure of Chinese indigenous sheep breeds，which would provide the basis for the conservation and utilization of germplasm of sheep.NETVIEW，PCA，STRUCTURE and NJ tree were used to analyze the Illumina Ovine SNP 50K chip data from 11 sheep breeds (resources) including Ujumqin sheep，Hu sheep，Tong sheep，Large Tailed Han sheep，Lop sheep，Kazakh sheep，Duolang sheep，Diqing sheep，Tibetan sheep from Qinghai，Tibetan sheep from Sichuan and Tibetan from Tibet.The results showed the indirect genetic relationship between Lop sheep and Ujumqin sheep and the direct genetic relationship between Ujumqin sheep and all Mongolia group sheep breeds except for Lop sheep.Lop sheep and Kazakh group sheep breeds had closer genetic relationship，Kazakh sheep and Duolang sheep existed a certain degree of differentiation.Diqing sheep could separate from Tibetan group.Tibetan sheep from Tibet could separate from the other regions of the Tibetan sheep，Tibetan sheep from Qinghai and Sichuan couldn’t be separated.The results suggest that NETVIEW calculate efficiently and can reflect basic historical facts，thus it can be used as the tool for population structure analysis in the future；Ujumqin sheep is one of the oldest breeds of Mongolia group sheep breeds in this experiment；Lop sheep and other breeds from Xinjiang cluster together due to mixed lineage；There exist differentiation tendency in different regions of Tibetan sheep，but the differentiation is not serious.

中图分类号:

S826
S813.3

袁泽湖，王慧华，胡师金，朱才业，赵福平，张莉，杜立新，魏彩虹. 利用50K芯片数据分析中国11个地方绵羊群体的遗传结构[J]. 畜牧兽医学报, 2016, 47(5): 899-908.

YUAN Ze-hu，WANG Hui-hua，HU Shi-jin，ZHU Cai-ye，ZHAO Fu-ping，ZHANG Li，DU Li-xin，WEI Cai-hong. Population Structure Analysis of Chinese Indigenous Sheep by 50K Chip Data[J]. ACTA VETERINARIA ET ZOOTECHNICA SINICA, 2016, 47(5): 899-908.

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